SCHEMBL531627

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5910980	0.88	ALDH3A1 (0.47)	ALDH1A1ALDH3A1LMNACYP1A2CYP2D6
	SCHEMBL5910982	0.88	ALDH3A1 (0.47)	ALDH1A1ALDH3A1LMNACYP1A2CYP2D6
	SCHEMBL2558621	0.87	GRIN2D (0.46)	ALDH1A1ALDH3A1LMNACYP1A2CYP2D6
	SCHEMBL531886	0.84	ALDH5A1 (0.48)	ALDH1A1ALDH3A1LMNACYP1A2CYP2D6
	SCHEMBL5350350	0.84	ALDH5A1 (0.48)	ALDH1A1ALDH3A1LMNACYP1A2CYP2D6
	SCHEMBL27965360	0.83	ALDH1A1 (0.46)	ALDH1A1LMNACYP2C19HTTSMN1; SMN2
	SCHEMBL2244840	0.82	KMT2A (0.57)	ALDH1A1LMNAMAPTHPGDSMN1; SMN2
	SCHEMBL13858407	0.80	ALDH1A1 (0.47)	ALDH1A1ALDH3A1LMNACYP1A2CYP2D6
	SCHEMBL10422981	0.79	ALDH1A1 (0.55)	ALDH1A1LMNACYP1A2CYP2D6CYP2C9
	SCHEMBL531957	0.79	ALDH1A1 (0.46)	ALDH1A1ALDH3A1LMNACYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.