Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | GPX4 | P36969 | 2/20 | 0.32 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975275 | 0.84 | SLC6A9 (0.39) | SLC6A9CNR1OPRD1GPX4KMT2A | |
| SCHEMBL975711 | 0.84 | SLC6A9 (0.37) | SLC6A9SCN9ACNR1OPRM1OPRD1 | |
| SCHEMBL977022 | 0.84 | SLC6A9 (0.37) | SLC6A9SCN9ACNR1OPRD1GPX4 | |
| SCHEMBL978430 | 0.83 | HPGD (0.38) | SLC6A9SCN9AOPRD1CA12CA1 | |
| SCHEMBL977237 | 0.82 | SLC6A9 (0.37) | SLC6A9OPRD1GPX4KMT2ACACNA1G | |
| SCHEMBL976058 | 0.81 | ATM (0.38) | SLC6A9CNR1ATM | |
| SCHEMBL979165 | 0.80 | SLC6A9 (0.36) | SLC6A9SCN9ACNR1OPRM1OPRD1 | |
| SCHEMBL975244 | 0.79 | WDR5 (0.44) | SLC6A9CNR1GPX4KMT2ACACNA1G | |
| SCHEMBL974202 | 0.79 | WDR5 (0.41) | SLC6A9SCN9ACNR1GPX4SCN7A | |
| SCHEMBL974408 | 0.79 | WDR5 (0.41) | SLC6A9SCN9ACNR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101945852-B | Azetidine derivatives, their preparation and their use in therapy | SANOFI AVENTIS | 2014-05-07 | — | — | CN | disclosed |