Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13431421 | 0.86 | BRD4 (0.51) | TP53MAOAMAOBPDE4APDE4B | |
| SCHEMBL27965887 | 0.81 | BRD4 (0.43) | TP53ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL3968668 | 0.81 | CDYL2 (0.49) | TP53MAOAPDE4APDE4BPDE4C | |
| SCHEMBL11079619 | 0.80 | BRD4 (0.47) | KMT2AKDM4EMEN1JAK2KIT | |
| SCHEMBL10066731 | 0.78 | TP53 (0.40) | TP53MAOAMAOBALDH1A1HPGD | |
| SCHEMBL27965965 | 0.78 | NQO2 (0.44) | TP53MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL18025745 | 0.77 | PDE4A (0.55) | TP53MAOAPDE4APDE4BPDE4C | |
| SCHEMBL18901276 | 0.76 | MAOA (0.46) | TP53MAOAMAOBALDH1A1MAPT | |
| SCHEMBL30564910 | 0.74 | JAK2 (0.53) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL3078111 | 0.74 | JAK2 (0.53) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103936537-B | A kind of phenol of golden catalysis and the selectivity c h bond functionalization method of aniline | EAST CHINA NORMAL UNIVERSITY (CN) | 2015-10-28 | — | — | CN | disclosed |
| CN-103936537-A | Method for performing gold-catalyzed selective C-H bond functionalization on phenol and aniline | UNIV EAST CHINA NORMAL | 2014-07-23 | — | — | CN | disclosed |