Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31167356 | 0.91 | SMYD3 (0.46) | SMYD3FGFR1GRM4HTR1AADRA1D | |
| SCHEMBL16134905 | 0.91 | SMYD3 (0.46) | SMYD3FGFR1GRM4HTR1AADRA1D | |
| SCHEMBL2174254 | 0.84 | GRM4 (0.47) | SMYD3GRM4HTR1AADRA1DADRA1A | |
| SCHEMBL1894839 | 0.84 | GRM4 (0.50) | SMYD3FGFR1GRM4HTR1AADRA1D | |
| SCHEMBL27007092 | 0.83 | TGFBR1 (0.43) | SMYD3FGFR1GRM4HTR1AADRA1D | |
| SCHEMBL27006910 | 0.82 | KDM4E (0.52) | SMYD3HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL25237561 | 0.82 | MAOA (0.46) | SMYD3GRM4HTR1AADRA1DADRA1A | |
| SCHEMBL28996585 | 0.82 | FERMT2 (0.45) | SMYD3FGFR1GRM4HTR1AADRA1D | |
| SCHEMBL27006871 | 0.82 | HTR1A (0.39) | SMYD3GRM4HTR1AADRA1DADRA1A | |
| SCHEMBL27969044 | 0.82 | MAOA (0.50) | GRM4MAPTKMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037266-A | Antibacterial chloroxoquinoline derivative | WANG ZIHOU | 2015-11-11 | — | — | CN | disclosed |
| CN-105017145-A | Chloroxoquinoline derivative with anti-tumor activity | WANG ZIHOU | 2015-11-04 | — | — | CN | disclosed |
| CN-103864680-B | Chloroxoquinoline derivative with antineoplastic activity | WANG ZIHOU (CN) | 2015-09-02 | — | — | CN | disclosed |
| CN-103864681-B | Chloroxoquinoline derivatives for antibacterial use | WANG ZIHOU (CN) | 2015-09-02 | — | — | CN | disclosed |
| CN-103864681-A | Chloroxoquinoline derivatives for antibacterial use | WANG ZIHOU | 2014-06-18 | — | — | CN | disclosed |
| CN-103864680-A | Chloroxoquinoline derivative with antineoplastic activity | WANG ZIHOU | 2014-06-18 | — | — | CN | disclosed |