Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624605 | 0.83 | SLC6A3 (0.40) | SLC6A3KDM4EALDH1A1 | |
| SCHEMBL27969194 | 0.80 | SLC6A3 (0.32) | SLC6A3KDM4EALDH1A1 | |
| SCHEMBL27828597 | 0.75 | SMN1; SMN2 (0.41) | SLC6A3KDM4EALDH1A1 | |
| SCHEMBL28277534 | 0.73 | SLC6A3 (0.34) | SLC6A3 | |
| SCHEMBL27652153 | 0.72 | SLC6A3 (0.41) | SLC6A3KDM4EALDH1A1 | |
| SCHEMBL20416995 | 0.68 | KDM4E (0.36) | SLC6A3KDM4EALDH1A1 | |
| SCHEMBL27612020 | 0.68 | GABRA5 (0.44) | KDM4EALDH1A1 | |
| SCHEMBL27882063 | 0.66 | GRM5 (0.32) | — | |
| SCHEMBL16095853 | 0.64 | SMN1; SMN2 (0.43) | KDM4EALDH1A1 | |
| SCHEMBL15469243 | 0.63 | HSD17B10 (0.34) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102414168-B | Bridged spiro [2.4] heptane derivatives as ALX receptor and/or FPRL2 agonists | ACTELION PHARMACEUTICALS LTD | 2014-05-21 | — | — | CN | disclosed |