Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.40 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27969494 | 0.82 | ALDH1A1 (0.38) | SMN1; SMN2 | |
| SCHEMBL28812775 | 0.76 | MAPT (0.40) | OXER1SMN1; SMN2 | |
| SCHEMBL28617610 | 0.75 | ALDH1A1 (0.47) | OPRL1OPRM1OPRD1OPRK1OXER1 | |
| SCHEMBL28613180 | 0.73 | OPRM1 (0.48) | OPRL1OPRM1OPRD1OPRK1OXER1 | |
| SCHEMBL27969497 | 0.73 | DRD4 (0.43) | OXER1SMN1; SMN2 | |
| SCHEMBL28623404 | 0.70 | OPRM1 (0.48) | OPRL1OPRM1OPRD1OPRK1OXER1 | |
| SCHEMBL28623424 | 0.67 | OPRM1 (0.53) | OPRL1OPRM1OPRD1OPRK1OXER1 | |
| SCHEMBL4672103 | 0.67 | OXER1 (0.52) | OXER1 | |
| SCHEMBL28047369 | 0.65 | AGTR1 (0.51) | OXER1SMN1; SMN2 | |
| SCHEMBL27745211 | 0.64 | OXER1 (0.49) | OXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103833642-A | Use of benzo five-membered azaheterocyclyl piperazine derivatives | LIAONING BEILEI BIOLOG PHARMACEUTICAL CO LTD | 2014-06-04 | — | — | CN | claimed |