SCHEMBL27969705

SCHEMBL27969705

c1cc2cccc3c4cccc5cccc(c(c1)c23)c54.c1ccc2c(c1)C2

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.61
CYP3A4 P08684 3/20 0.61
ALDH1A1 P00352 9/20 0.56
HSD17B10 Q99714 8/20 0.56
CYP1A2 P05177 7/20 0.56
HPGD P15428 6/20 0.56
THRB P10828 1/20 0.56
MAOA P21397 2/20 0.45
ERBB2 P04626 1/20 0.45
FYN P06241 1/20 0.45
ACHE P22303 1/20 0.45
AHR P35869 1/20 0.45
KDM4E B2RXH2 2/20 0.43
CYP1A1 P04798 1/20 0.41
CYP1B1 Q16678 1/20 0.41
MAPK1 P28482 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ATM Q13315 1/20 0.40
CASP1 P29466 1/20 0.40
HIF1A Q16665 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL7752293 0.89 TSHR (0.54) TSHRCYP3A4ALDH1A1HSD17B10CYP1A2
Fluorene SCHEMBL28556215 0.89 TSHR (0.54) TSHRCYP3A4ALDH1A1HSD17B10CYP1A2
Xanthene SCHEMBL27581910 0.83 MAOA (0.65) TSHRCYP3A4ALDH1A1HSD17B10CYP1A2
Anthrone SCHEMBL27887608 0.82 MAOA (0.67) TSHRCYP3A4ALDH1A1HSD17B10CYP1A2
Triphenylene SCHEMBL28972585 0.81 ALDH1A1 (0.82) TSHRCYP3A4ALDH1A1HSD17B10CYP1A2
Triphenylene SCHEMBL5501206 0.81 ALDH1A1 (0.82) TSHRCYP3A4ALDH1A1HSD17B10CYP1A2
Naphthalene SCHEMBL87628 0.81 ALDH1A1 (0.72) TSHRCYP3A4ALDH1A1HSD17B10CYP1A2
SCHEMBL634848 0.81 ALDH1A1 (0.71) TSHRCYP3A4ALDH1A1HSD17B10CYP1A2
SCHEMBL26440 0.81 ALDH1A1 (0.71) TSHRCYP3A4ALDH1A1HSD17B10CYP1A2
SCHEMBL29906043 0.81 ALDH1A1 (0.71) TSHRCYP3A4ALDH1A1HSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104248977-A Method for preparation of composite photocatalyst from photosensitizer and use thereof XINJIANG TECH INST PHYSICS CAS 2014-12-31 CN claimed