Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorene SCHEMBL28556215 | 1.00 | TSHR (0.54) | TSHRCYP3A4ALDH1A1HSD17B10HPGD | |
| Benzo[E]Pyrene SCHEMBL28074705 | 0.92 | ALDH1A1 (0.64) | TSHRCYP3A4ALDH1A1HSD17B10HPGD | |
| SCHEMBL27969705 | 0.89 | TSHR (0.61) | TSHRCYP3A4ALDH1A1HSD17B10HPGD | |
| Anthrone SCHEMBL27887608 | 0.88 | MAOA (0.67) | TSHRCYP3A4ALDH1A1HSD17B10HPGD | |
| Pyrene SCHEMBL5793586 | 0.88 | TSHR (0.56) | TSHRCYP3A4ALDH1A1HSD17B10HPGD | |
| SCHEMBL4853975 | 0.88 | TSHR (0.47) | TSHRCYP3A4ALDH1A1HSD17B10HPGD | |
| Pyrene SCHEMBL2125072 | 0.86 | TSHR (0.65) | TSHRCYP3A4ALDH1A1HSD17B10HPGD | |
| SCHEMBL29573523 | 0.84 | TSHR (0.62) | TSHRCYP3A4ALDH1A1HSD17B10HPGD | |
| SCHEMBL3766146 | 0.84 | TSHR (0.62) | TSHRCYP3A4ALDH1A1HSD17B10HPGD | |
| Fluorene SCHEMBL28714196 | 0.84 | MAOA (0.48) | TSHRCYP3A4ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112510159-A | Heterocyclic compound and organic light-emitting device including the same | 三星显示有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-105431956-A | Electro-optical device and use thereof | MERCK PATENT GMBH | 2016-03-23 | — | — | CN | disclosed |
| EP-2736881-A1 | PROCESS FOR PRODUCING N-(HETERO)ARYLAZOLES | Takasago International Corporation (JP) | 2014-06-04 | — | — | EP | disclosed |
| CN-103270616-A | Organic electroluminescent device | MERCK PATENT GMBH | 2013-08-28 | — | — | CN | disclosed |
| WO-2013032035-A1 | PROCESS FOR PRODUCING N-(HETERO)ARYLAZOLES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-03-07 | — | — | WO | disclosed |
| CN-101503507-A | Conjugated polymer material of fluorine, pyrene and perylene and preparation thereof | UNIV NANJING POSTS & TELECOMM (CN) | 2009-08-12 | — | — | CN | disclosed |
| WO-2001042331-A1 | FLUORENE-PERYLENE COPOLYMERS AND USES THEREOF | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2001-06-14 | — | — | WO | disclosed |