SCHEMBL27969874

SCHEMBL27969874

CS(=O)(=O)OCCC(N)C(=O)OCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
SLC1A1 P43005 2/20 0.44
SLC1A3 P43003 1/20 0.44
CA1 P00915 4/20 0.43
CA2 P00918 4/20 0.43
CA9 Q16790 3/20 0.43
CA12 O43570 2/20 0.43
IDO1 P14902 1/20 0.43
LTA4H P09960 2/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A3 Q01959 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
SLC15A1 P46059 2/20 0.40
LAP3 P28838 1/20 0.40
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31479931 0.90 DPP8 (0.41) ALDH1A1SLC1A1SLC1A3CA1CA2
SCHEMBL27395771 0.82 LMNA (0.50) ALDH1A1SLC1A1SLC1A3CA1CA2
SCHEMBL7064408 0.82 ALDH1A1 (0.44) ALDH1A1CA1CA2CA9CA12
SCHEMBL7268383 0.81 ALDH1A1 (0.62) ALDH1A1SLC1A1SLC1A3IDO1LTA4H
SCHEMBL10678429 0.81 SLC1A1 (0.54) ALDH1A1SLC1A1SLC1A3IDO1LTA4H
SCHEMBL27464981 0.80 CCR6 (0.40) ALDH1A1CA1CA2CA9CA12
SCHEMBL30844639 0.80 SLC1A1 (0.49) ALDH1A1SLC1A1SLC1A3IDO1LTA4H
Hydrochloric Acid SCHEMBL7268375 0.80 ALDH1A1 (0.60) ALDH1A1SLC1A1SLC1A3IDO1LTA4H
SCHEMBL7715747 0.80 CA1 (0.51) ALDH1A1SLC1A1SLC1A3CA1CA2
SCHEMBL14196105 0.80 SLC1A1 (0.48) ALDH1A1SLC1A1SLC1A3IDO1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104017008-A Boron-containing small molecules ANACOR PHARMACEUTICALS INC 2014-09-03 CN disclosed