Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27971282 | 0.81 | SMN1; SMN2 (0.51) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20651045 | 0.79 | MEN1 (0.44) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27985272 | 0.76 | RAB9A (0.51) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL20651039 | 0.76 | SMN1; SMN2 (0.37) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20651092 | 0.73 | HTT (0.44) | POLBALDH1A1SMN1; SMN2RAB9AHPGD | |
| SCHEMBL28564941 | 0.72 | SMN1; SMN2 (0.63) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27971285 | 0.72 | MAPT (0.59) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27971318 | 0.72 | NPC1 (0.59) | ALDH1A1SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL9499605 | 0.71 | POLB (0.56) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL25962674 | 0.70 | ALDH1A1 (0.55) | POLBALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104045605-A | Phenoxymethyl sulfone derivatives as well as synthesis method and application of phenoxymethyl sulfone derivatives | UNIV GUIZHOU | 2014-09-17 | — | — | CN | claimed |
| CN-104045605-A | Phenoxymethyl sulfone derivatives as well as synthesis method and application of phenoxymethyl sulfone derivatives | UNIV GUIZHOU | 2014-09-17 | — | — | CN | disclosed |