Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28572241 | 0.83 | L3MBTL1 (0.51) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL28568101 | 0.83 | APP (0.47) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL28568098 | 0.83 | CPB1 (0.46) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL28568107 | 0.83 | MAPT (0.60) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL10898999 | 0.83 | TDP1 (0.55) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL28571149 | 0.83 | HPGD (0.47) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL31522242 | 0.81 | TDP1 (0.60) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL31522247 | 0.81 | ALDH1A1 (0.60) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL28562808 | 0.79 | POLB (0.63) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL28568102 | 0.77 | NPC1 (0.49) | SMN1; SMN2POLBALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898222-B | Oxadiazole compound and preparation method and application thereof | 长沙理工大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-112898222-A | Oxadiazole compound and preparation method and application thereof | 长沙理工大学 | 2021-06-04 | — | — | CN | disclosed |