Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11460627 | 0.85 | HMGCR (0.50) | HMGCRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL9645065 | 0.82 | CA9 (0.49) | HMGCRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL313281 | 0.81 | ALDH1A1 (0.54) | LMNAMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL312482 | 0.81 | ALDH1A1 (0.46) | LMNAMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL314560 | 0.80 | GAA (0.53) | LMNAMEN1KMT2AALDH1A1PDE4D | |
| SCHEMBL24069248 | 0.79 | PDE4D (0.49) | HMGCRLMNAMEN1KMT2APDE4D | |
| SCHEMBL28299854 | 0.79 | HMGCR (0.51) | HMGCRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL27787230 | 0.78 | HSP90AB1 (0.49) | HMGCRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL17653405 | 0.77 | CTSD (0.49) | HMGCRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL9720636 | 0.73 | LMNA (0.65) | HMGCRLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101977915-B | Macrocyclic serine protease inhibitors | IDENIX PHARMACEUTICALS INC (US) | 2014-08-13 | — | — | CN | disclosed |