Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27972313 | 0.90 | KCNJ5 (0.50) | PTPN1SMN1; SMN2ROCK2KMT2ALMNA | |
| SCHEMBL27972580 | 0.85 | BCHE (0.49) | SMN1; SMN2KMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL28260015 | 0.85 | HCAR2 (0.41) | SMN1; SMN2KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL28259976 | 0.85 | KCNJ5 (0.39) | PTPN1RECQLSMN1; SMN2ROCK2KMT2A | |
| SCHEMBL27972283 | 0.83 | MEN1 (0.41) | SMN1; SMN2KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL27972549 | 0.82 | SMO (0.53) | SMN1; SMN2KMT2ALMNAMEN1NPC1 | |
| SCHEMBL28259946 | 0.82 | PTPN1 (0.42) | PTPN1RECQLSMN1; SMN2ROCK2KMT2A | |
| SCHEMBL27972587 | 0.80 | ALDH1A1 (0.53) | SMN1; SMN2KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL27972589 | 0.80 | KCNJ5 (0.57) | ROCK2LMNAALDH1A1POLBANO1 | |
| SCHEMBL28425371 | 0.79 | RAB9A (0.47) | SMN1; SMN2KMT2ALMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104066724-A | P2X4 receptor antagonists | NIPPON CHEMIPHAR CO | 2014-09-24 | — | — | CN | disclosed |