SCHEMBL27972347

SCHEMBL27972347

NC(CC(=O)O)C(=O)OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SYNJ2 O15056 2/20 0.41
▸ KDM4E B2RXH2 2/20 0.41
▸ RECQL P46063 2/20 0.41
▸ ABL1 P00519 1/20 0.41
▸ ALPL P05186 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ ALPI P09923 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ ALPG P10696 1/20 0.41
▸ PABPC1 P11940 1/20 0.41
▸ GALK1 P51570 1/20 0.41
▸ CASP7 P55210 1/20 0.41
▸ CASP6 P55212 1/20 0.41
▸ MCL1 Q07820 1/20 0.41
▸ RIN1 Q13671 1/20 0.41
▸ EIF4H Q15056 1/20 0.41
▸ LGALS8 O00214 1/20 0.39
▸ LMNA P02545 1/20 0.38
▸ ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL28584405 0.97 SYNJ2 (0.40) SYNJ2KDM4ERECQLABL1ALPL
SCHEMBL2066639 0.89 LMNA (0.40) KDM4ERECQLLGALS8LMNAALOX15
SCHEMBL29603364 0.88 SYNJ2 (0.40) SYNJ2KDM4ERECQLABL1ALPL
SCHEMBL8508842 0.86 LMNA (0.38) KDM4ERECQLLGALS8LMNAALOX15
SCHEMBL8508841 0.86 LMNA (0.38) KDM4ERECQLLGALS8LMNAALOX15
SCHEMBL25339181 0.83 CD209 (0.40) SYNJ2KDM4ERECQLABL1ALPL
SCHEMBL25308944 0.81 ALDH1A1 (0.42) KDM4ERECQLLGALS8LMNAALOX15
Hydrochloric Acid SCHEMBL28503443 0.80 SYNJ2 (0.45) SYNJ2KDM4ERECQLABL1ALPL
Hydrochloric Acid SCHEMBL28889007 0.80 ALDH1A1 (0.41) KDM4ERECQLLGALS8LMNAALOX15
SCHEMBL2065875 0.80 ALDH1A1 (0.41) KDM4ELGALS8LMNAALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079802-A Cationic lipids and compositions thereof — 2026-05-26 — — CN claimed
CN-114929205-B Lipid nanoparticle compositions comprising end-capped DNA and cleavable lipids and methods of use thereof 世代生物公司 2024-09-03 — — CN claimed
CN-118318045-A Liver-specific expression cassette, vector and use thereof for expression of therapeutic proteins 世代生物公司 2024-07-09 — — CN claimed
CN-114787127-B Ionizable lipids and nanoparticle compositions thereof 世代生物公司 2024-04-26 — — CN claimed
CN-117897143-A APOE and APOB modified lipid nanoparticle compositions and uses thereof 世代生物公司 2024-04-16 — — CN claimed
CN-117642380-A Cationic lipids and compositions thereof 世代生物公司 2024-03-01 — — CN claimed
CN-117083070-A Proparvovirus and tetrapparvovirus compositions and methods for gene therapy 森特尼医疗公司 2023-11-17 — — CN claimed
CN-116437964-A Methods for encapsulating polynucleotides into reduced size lipid nanoparticles and novel formulations thereof 世代生物公司 2023-07-14 — — CN claimed
CN-115298184-A Heterocyclic RIP1 inhibiting compounds 里格尔药品股份有限公司 2022-11-04 — — CN claimed
CN-114929205-A Lipid nanoparticle compositions comprising terminally-blocked DNA and cleavable lipids and methods of use thereof 世代生物公司 2022-08-19 — — CN claimed
CN-114761398-A Heterocyclic RIP1 kinase inhibitors 里格尔药品股份有限公司 2022-07-15 — — CN claimed
CN-114728958-A RIP1 inhibiting compounds and methods of making and using the same 里格尔药品股份有限公司 2022-07-08 — — CN claimed
CN-103328646-B Mannosidase capable of uncapping mannose-1-phosphate-6-mannose linkages and demannosylating phosphorylated N-glycans and a method of promoting mammalian cellular uptake of glycoproteins 奥克西雷恩英国有限公司 2021-06-18 — — CN claimed
CN-112513071-A Gene therapy constructs and methods of use 阿米库斯治疗学公司 2021-03-16 — — CN claimed
CN-107523219-A Chemical Mechanical Polishing (CMP) of Cobalt-Containing Substrates 弗萨姆材料美国有限责任公司 2017-12-29 — — CN claimed
CN-105295737-A Chemical mechanical polishing (CMP) of cobalt-containing substrate AIR PROD & CHEM 2016-02-03 — — CN claimed
CN-122079802-A Cationic lipids and compositions thereof — 2026-05-26 — — CN disclosed
CN-114728958-B RIP1 inhibitory compounds and methods of making and using the same 里格尔药品股份有限公司 2025-05-02 — — CN disclosed
CN-105073745-A Glucosylceramide synthase inhibitors GENZYME CORP 2015-11-18 — — CN disclosed
CN-103917094-A Glucosylceramide synthase inhibitors GENZYME CORP 2014-07-09 — — CN disclosed
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