SCHEMBL27972729

SCHEMBL27972729

COC(=O)c1nc([N+](=O)[O-])ccc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.44
CA12 O43570 3/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA7 P43166 3/20 0.40
CA9 Q16790 3/20 0.40
CA14 Q9ULX7 3/20 0.40
XDH P47989 1/20 0.40
POLB P06746 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ERN1 O75460 1/20 0.37
MAPT P10636 4/20 0.37
ALDH1A1 P00352 3/20 0.37
LCK P06239 2/20 0.37
LMNA P02545 2/20 0.37
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
GAA P10253 1/20 0.37
VCAM1 P19320 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27972725 0.84 MAPT (0.50) CA12CA1CA2CA7CA9
SCHEMBL187255 0.82 TDP1 (0.44) NPSR1POLBMEN1KMT2AALDH1A1
SCHEMBL27971913 0.81 PTGS1 (0.40) CA1CA2ERN1MAPTALDH1A1
SCHEMBL29829085 0.75 NPSR1 (0.50) NPSR1CA12CA1CA2CA7
SCHEMBL388845 0.75 NPSR1 (0.50) NPSR1CA12CA1CA2CA7
SCHEMBL26140305 0.75 NPSR1 (0.50) NPSR1CA12CA1CA2CA7
SCHEMBL3947679 0.75 GRM5 (0.53) NPSR1CA12CA1CA2CA7
SCHEMBL23041103 0.74 ALDH1A1 (0.50) CA12CA1CA2CA9MEN1
SCHEMBL29769754 0.74 ALDH1A1 (0.50) CA12CA1CA2CA9MEN1
SCHEMBL29625298 0.74 NPSR1 (0.48) NPSR1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104016912-B The synthesis separating and purifying method of 6-nitro-3-hydroxyl-2-pyridine carboxylic acid XIHUA UNIVERSITY (CN) 2015-10-21 CN disclosed
CN-104016912-A Synthesizing, separating and purifying method for 6-nitryl-3-hydroxyl-2-pyridinecarboxylic acid UNIV XIHUA 2014-09-03 CN disclosed