Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27972729 | 0.84 | NPSR1 (0.44) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL25248606 | 0.76 | CA12 (0.49) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL31236724 | 0.76 | CA12 (0.49) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL27971913 | 0.76 | PTGS1 (0.40) | MAPTPTGS1PTGS2CA1CA2 | |
| SCHEMBL30828955 | 0.74 | L3MBTL1 (0.49) | MAPTPTGS1PTGS2CA12CA1 | |
| SCHEMBL25566401 | 0.72 | PTGS1 (0.47) | MAPTPTGS1PTGS2MITFRAB9A | |
| SCHEMBL117763 | 0.72 | CTSB (0.44) | MAPTGAAL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30227675 | 0.72 | CTSB (0.44) | MAPTGAAL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8926094 | 0.72 | CYP1A2 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13405555 | 0.71 | SMN1; SMN2 (0.51) | MAPTMITFRAB9AGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016912-B | The synthesis separating and purifying method of 6-nitro-3-hydroxyl-2-pyridine carboxylic acid | XIHUA UNIVERSITY (CN) | 2015-10-21 | — | — | CN | disclosed |
| CN-104016912-A | Synthesizing, separating and purifying method for 6-nitryl-3-hydroxyl-2-pyridinecarboxylic acid | UNIV XIHUA | 2014-09-03 | — | — | CN | disclosed |