Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.30 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27973179 | 0.85 | LMNA (0.34) | DAOPLAUALDH1A1KMT2ALMNA | |
| SCHEMBL15004234 | 0.83 | DAO (0.36) | DAOPLAUKMT2ALMNACYP2C9 | |
| SCHEMBL27642261 | 0.82 | DAO (0.33) | DAOCCR4 | |
| SCHEMBL12140992 | 0.81 | PLAU (0.43) | DAOPLAUKMT2ALMNACYP2C9 | |
| SCHEMBL676712 | 0.78 | DAO (0.33) | DAOPLAULMNACYP2C9TSHR | |
| SCHEMBL27641249 | 0.78 | CA2 (0.33) | DAOLMNACYP2C9TSHRAPEX1 | |
| SCHEMBL676596 | 0.78 | DAO (0.33) | DAOPLAULMNACYP2C9TSHR | |
| SCHEMBL25348528 | 0.75 | CA2 (0.34) | DAOLMNACYP2C9TSHRAPEX1 | |
| SCHEMBL27955259 | 0.75 | CA2 (0.34) | AGXTHTTRECQLGAAMAPT | |
| SCHEMBL14853414 | 0.75 | CCNB2 (0.32) | DAOPLAULMNACYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102741227-B | Aryl benzylamine compounds | NOVARTIS AG | 2014-07-30 | — | — | CN | disclosed |