Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 11/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | S100A9 | P06702 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25348528 | 0.82 | CA2 (0.34) | DAOCCR4LMNACYP2C9TSHR | |
| SCHEMBL15004234 | 0.81 | DAO (0.36) | DAOPLAUCCR4LMNACYP2C9 | |
| SCHEMBL12140992 | 0.79 | PLAU (0.43) | DAOPLAUCCR4LMNACYP2C9 | |
| SCHEMBL21634877 | 0.79 | GAA (0.32) | TSHR | |
| SCHEMBL27897072 | 0.78 | KMT2A (0.37) | SMN1; SMN2PIK3CAMTOR | |
| SCHEMBL27973006 | 0.78 | DAO (0.34) | DAOPLAUCCR4LMNACYP2C9 | |
| SCHEMBL676596 | 0.76 | DAO (0.33) | DAOPLAUCCR4LMNACYP2C9 | |
| SCHEMBL27641249 | 0.76 | CA2 (0.33) | DAOCCR4LMNACYP2C9TSHR | |
| SCHEMBL14853132 | 0.76 | PIK3CA (0.34) | DAOPIK3CAMTOR | |
| SCHEMBL27973179 | 0.75 | LMNA (0.34) | DAOPLAUCCR4LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112441967-B | Preparation method of methoxybenzene cry bacterial intermediate | 南北兄弟药业投资有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-116640092-A | Benzyloxy substituted bipyridine methanone compound and application thereof | 南北兄弟药业投资有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-112441967-A | Preparation method of methoxybenzene cry bacterial intermediate | 南北兄弟药业投资有限公司 | 2021-03-05 | — | — | CN | disclosed |
| US-20170188579-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | ISHIHARA SANGYO KAISHA (JP) | 2017-07-06 | — | — | US | disclosed |
| US-9655362-B2 | Fungicidal composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2017-05-23 | — | — | US | disclosed |
| EP-2769980-B1 | PYRAZOLOQUINOLINE DERIVATIVE AS PDE9 INHIBITORS | EISAI R&D MAN CO LTD (JP) | 2016-02-03 | — | — | EP | disclosed |
| EP-2769980-B1 | PYRAZOLOQUINOLINE DERIVATIVE AS PDE9 INHIBITORS | EISAI R&D MAN CO LTD (JP) | 2016-02-03 | — | — | EP | disclosed |
| EP-1679003-B1 | BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE | ISHIHARA SANGYO KAISHA (JP) | 2015-04-15 | — | — | EP | disclosed |
| EP-2769980-A1 | PYRAZOLOQUINOLINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2014-08-27 | — | — | EP | disclosed |
| EP-2769980-A1 | PYRAZOLOQUINOLINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2014-08-27 | — | — | EP | disclosed |
| US-20130143907-A1 | PYRAZOLOQUINOLINE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-06-06 | — | — | US | disclosed |
| US-20130143907-A1 | PYRAZOLOQUINOLINE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-06-06 | — | — | US | disclosed |
| US-20130143907-A1 | PYRAZOLOQUINOLINE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-06-06 | — | — | US | disclosed |
| WO-2013051639-A1 | PYRAZOLOQUINOLINE DERIVATIVE | エーザイ・アール・アンド・ディー・マネジメント株式会社 (JP) | 2013-04-11 | — | — | WO | disclosed |
| US-20120135088-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
| US-20110280959-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2011-11-17 | — | — | US | disclosed |
| EP-2338335-A1 | Preparation of fungicidal benzoylpyridine derivatives | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2011-06-29 | — | — | EP | disclosed |
| US-20090247763-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-10-01 | — | — | US | disclosed |
| US-20060194849-A1 | Fungicidal composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-08-31 | — | — | US | disclosed |
| EP-1679003-A1 | BACTERICIDE COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247763-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | CBR3, CBR1, CNPY2 | DAO 9/4885PLAU 4859/4885CCR4 1611/4885 |
| US-20120135088-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | CBR3, CNPY2, PAH | DAO 14/4885PLAU 4842/4885CCR4 1182/4885 |
| US-20130143907-A1 | PYRAZOLOQUINOLINE DERIVATIVES | PDE2A, PDE3A, PDE3B | DAO 1598/4885PLAU 2095/4885CCR4 3760/4885 |
| US-20110280959-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | CBR3, CNPY2, PAH | DAO 14/4885PLAU 4842/4885CCR4 1182/4885 |
| US-20060194849-A1 | Fungicidal composition and method for controlling plant diseases | CBR3, CNPY2, PAH | DAO 14/4885PLAU 4842/4885CCR4 1182/4885 |
| US-20170188579-A1 | FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | CBR3, CNPY2, PAH | DAO 14/4885PLAU 4842/4885CCR4 1182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.