Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497026 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| SCHEMBL6492647 | 0.86 | ALDH1A1 (0.52) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| Sulfuric Acid SCHEMBL10708662 | 0.83 | CYP1A2 (0.48) | ALDH1A1CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL30565328 | 0.81 | KEAP1 (0.49) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| SCHEMBL28349693 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| SCHEMBL28349697 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| SCHEMBL7425681 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| SCHEMBL333604 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| SCHEMBL875437 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| SCHEMBL11106443 | 0.80 | CYP1A2 (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107151245-B | A kind of preparation method of levo-praziquantel | 苏州同力生物医药有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-104045568-A | Novel process for synthesizing -1- (naphthalene-1-yl) ethylamine | ENANTIOTECH CORP LTD | 2014-09-17 | — | — | CN | disclosed |