Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28349697 | 0.86 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| SCHEMBL28349693 | 0.86 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| SCHEMBL7425681 | 0.86 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| SCHEMBL497026 | 0.86 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| SCHEMBL30565328 | 0.86 | KEAP1 (0.49) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| SCHEMBL9516570 | 0.83 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| Sulfuric Acid SCHEMBL10708662 | 0.80 | CYP1A2 (0.48) | ALDH1A1CYP1A2CYP2C9CYP2C19CA1 | |
| SCHEMBL15562148 | 0.80 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| SCHEMBL12462064 | 0.80 | KEAP1 (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| SCHEMBL12462066 | 0.80 | KEAP1 (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858603-B2 | Acetindine derivatives, their preparation and medicaments containing them | AVENTIS PHARMA S.A. (FR) | 2005-02-22 | — | — | US | disclosed |
| US-20030162808-A1 | Acetindine derivatives, their preparation and medicaments containing them | AVENTIS PHARMA S.A. (FR) | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162808-A1 | Acetindine derivatives, their preparation and medicaments containing them | ADRA1D, ADRB2, AZI2 | ALDH1A1 32/4885CYP1A2 14/4885CYP2C9 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.