Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.48 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.47 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5536929 | 0.81 | SLC6A4 (0.61) | QDPRSLC6A4TGFBR1ACVR1EHMT2 | |
| SCHEMBL30108183 | 0.81 | QDPR (0.50) | QDPRSLC6A4TGFBR1ACVR1EHMT2 | |
| SCHEMBL7033282 | 0.80 | QDPR (0.56) | QDPRSLC6A4TGFBR1ACVR1EHMT2 | |
| Hydrochloric Acid SCHEMBL7030177 | 0.80 | QDPR (0.56) | QDPRSLC6A4TGFBR1ACVR1EHMT2 | |
| SCHEMBL28512145 | 0.80 | SLC6A4 (0.55) | QDPRSLC6A4TGFBR1ACVR1EHMT2 | |
| SCHEMBL28848491 | 0.80 | QDPR (0.46) | QDPRSLC6A4TGFBR1ACVR1EHMT2 | |
| SCHEMBL30292493 | 0.79 | QDPR (0.48) | QDPRSLC6A4TGFBR1ACVR1EHMT2 | |
| SCHEMBL5547709 | 0.79 | QDPR (0.54) | QDPRSLC6A4TGFBR1ACVR1 | |
| SCHEMBL20934696 | 0.78 | TGFBR1 (0.47) | QDPRSLC6A4TGFBR1ACVR1EHMT2 | |
| SCHEMBL298857 | 0.75 | QDPR (0.54) | QDPRSLC6A4TGFBR1ACVR1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102458398-B | Pyrrolidine-substituted flavones as radio-sensitizers for use in the treatment of cancer | PIRAMAL LIFE SCIENCES LTD | 2014-07-16 | — | — | CN | disclosed |