Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.47 |
| ▸ | HTR2C | P28335 | 8/20 | 0.47 |
| ▸ | HTR2B | P41595 | 8/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27919511 | 0.84 | HTR2C (0.36) | HTR2AHTR2CHTR2BDRD2DRD1 | |
| SCHEMBL27919507 | 0.80 | HTR2C (0.50) | HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL27343433 | 0.80 | HTR2C (0.49) | HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL27818616 | 0.77 | CA1 (0.50) | DRD2KDM1AMAOAKDM4ECYP2C9 | |
| SCHEMBL27901805 | 0.76 | MAOA (0.62) | MAOATSHRHSD17B10 | |
| SCHEMBL28323938 | 0.74 | ADRB2 (0.36) | HTR2AHTR2CHTR2BDRD2KDM1A | |
| SCHEMBL17732723 | 0.73 | KDM1A (0.43) | DRD2KDM1AMAOAKDM4ECYP2C9 | |
| SCHEMBL27797398 | 0.73 | KDM4C (0.41) | HTR2AHTR2CKDM1A | |
| SCHEMBL17732769 | 0.73 | KDM1A (0.43) | DRD2KDM1AMAOAKDM4ECYP2C9 | |
| SCHEMBL27919637 | 0.73 | TBXA2R (0.37) | HTR2AHTR2CHTR2BDRD1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103108871-B | 17a-hydroxylase/c17,20-lyase inhibitors | NOVARTIS AG | 2014-09-10 | — | — | CN | disclosed |