Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744434 | 0.88 | L3MBTL1 (0.64) | MAPTKMT2AL3MBTL1LMNACYP1A2 | |
| SCHEMBL28719044 | 0.84 | ALDH1A1 (0.57) | MAPTKMT2AL3MBTL1LMNAHDAC1 | |
| SCHEMBL11709225 | 0.84 | GAA (0.61) | MAPTKMT2AL3MBTL1LMNAHDAC1 | |
| SCHEMBL659139 | 0.82 | CA12 (0.56) | MAPTKMT2AL3MBTL1LMNAHDAC1 | |
| SCHEMBL726435 | 0.79 | TDP1 (0.63) | MAPTLMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL24703892 | 0.77 | MAPK1 (0.49) | MAPTKMT2AL3MBTL1LMNAHDAC6 | |
| SCHEMBL11710335 | 0.76 | KDM4E (0.62) | L3MBTL1KDM4ECYP2D6MAPK1SMN1; SMN2 | |
| SCHEMBL31161094 | 0.76 | L3MBTL1 (0.75) | MAPTKMT2AL3MBTL1LMNAKDM4E | |
| SCHEMBL7285060 | 0.76 | L3MBTL1 (0.75) | MAPTKMT2AL3MBTL1LMNAKDM4E | |
| SCHEMBL10765868 | 0.76 | TDP1 (0.59) | MAPTLMNACYP1A2TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103974937-A | Novel adipogenesis inhibitor compounds | FABRE PIERRE DERMO COSMETIQUE | 2014-08-06 | — | — | CN | disclosed |