Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14593279 | 0.80 | TRPA1 (0.57) | ACHEALDH1A1MAPK1ACP3AOC3 | |
| SCHEMBL321883 | 0.76 | ACHE (0.52) | ACHEALDH1A1MAPK1ACP3AOC3 | |
| SCHEMBL4438842 | 0.76 | ACHE (0.52) | ACHEALDH1A1MAPK1ACP3AOC3 | |
| SCHEMBL7203410 | 0.76 | ACP3 (0.43) | ACHEALDH1A1MAPK1ACP3AOC3 | |
| SCHEMBL11068902 | 0.74 | ACHE (0.41) | ACHEALDH1A1MAPK1ACP3AOC3 | |
| SCHEMBL30647223 | 0.74 | ACHE (0.50) | ACHEALDH1A1MAPK1ACP3AOC3 | |
| SCHEMBL15531691 | 0.74 | ACHE (0.50) | ACHEALDH1A1MAPK1ACP3AOC3 | |
| SCHEMBL30647112 | 0.74 | ACHE (0.50) | ACHEALDH1A1MAPK1ACP3AOC3 | |
| SCHEMBL1812638 | 0.74 | ACHE (0.50) | ACHEALDH1A1MAPK1ACP3AOC3 | |
| SCHEMBL4184813 | 0.73 | TRPA1 (0.58) | ALDH1A1TRPA1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104387389-B | 1,2,3-triazole-flavone compound-matrine ternary yoke connection thing and purposes | 中国医学科学院生物医学工程研究所 | 2016-08-03 | — | — | CN | disclosed |
| CN-104387389-A | 1,2,3-Triazole-flavonoid compound-sophocarpidine ternary conjugate and use | INST BIOMEDICAL ENG CAMS | 2015-03-04 | — | — | CN | disclosed |