Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 7/20 | 0.42 |
| ▸ | MAOA | P21397 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl-4-Amine SCHEMBL8808746 | 0.86 | TDP1 (0.65) | TSHRTDP1CYP3A4TP53ALDH1A1 | |
| Aniline SCHEMBL1767900 | 0.83 | TSHR (0.73) | TSHRTDP1CYP3A4TP53ALDH1A1 | |
| Ether SCHEMBL28632893 | 0.81 | ALDH1A1 (0.56) | TSHRTDP1CYP3A4TP53ALDH1A1 | |
| Aniline SCHEMBL27858423 | 0.80 | TSHR (0.69) | TSHRTDP1CYP3A4TP53ALDH1A1 | |
| Aniline SCHEMBL4922167 | 0.80 | TSHR (0.69) | TSHRTDP1CYP3A4TP53ALDH1A1 | |
| Aniline SCHEMBL11815890 | 0.80 | TSHR (0.69) | TSHRTDP1CYP3A4TP53ALDH1A1 | |
| Aniline SCHEMBL17710404 | 0.80 | TSHR (0.69) | TSHRTDP1CYP3A4TP53ALDH1A1 | |
| Aniline SCHEMBL27639272 | 0.80 | TSHR (0.52) | TSHRTDP1CYP3A4TP53ALDH1A1 | |
| Benzidine SCHEMBL1056565 | 0.79 | TDP1 (0.58) | TSHRTDP1CYP3A4TP53ALDH1A1 | |
| Aniline SCHEMBL2797779 | 0.78 | TSHR (0.50) | TSHRTDP1CYP3A4TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747977-B | Arylamine ether metal complexes, and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-111747977-A | Arylamine ether metal complexes, and preparation method and application thereof | 万华化学集团股份有限公司 | 2020-10-09 | — | — | CN | claimed |
| CN-111747977-B | Arylamine ether metal complexes, and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-111747977-B | Arylamine ether metal complexes, and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-111662403-B | Cascade catalytic system and method for preparing LLDPE (Linear Low Density polyethylene) by using same | 万华化学集团股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-111747977-A | Arylamine ether metal complexes, and preparation method and application thereof | 万华化学集团股份有限公司 | 2020-10-09 | — | — | CN | disclosed |
| CN-111747977-A | Arylamine ether metal complexes, and preparation method and application thereof | 万华化学集团股份有限公司 | 2020-10-09 | — | — | CN | disclosed |
| CN-111662403-A | Cascade catalytic system and method for preparing LLDPE (Linear Low Density polyethylene) by using same | 万华化学集团股份有限公司 | 2020-09-15 | — | — | CN | disclosed |
| US-7872155-B2 | Method of deprotection of alkyl arylamine ethers | XEROX CORPORATION (US) | 2011-01-18 | — | — | US | disclosed |
| US-20090131721-A1 | METHOD OF DEPROTECTION OF ALKYL ARYLAMINE ETHERS | XEROX CORPORATION (US) | 2009-05-21 | — | — | US | disclosed |
| EP-1046654-B1 | Olefin polymerization catalysts and olefin polymer production methods using said olefin polymerization catalysts | JSR CORP (JP) | 2005-06-29 | — | — | EP | disclosed |
| US-6525150-B1 | Such as vanadium 2,2'-thiobis(6-t-butyl-4-methylphenyl) oxychloride complex, trimethylaluminum and N,N-dimethyl-anilinium tetrakis(pentafluorophenyl)borate; high degree of copolymerization | JSR CORPORATION (JP) | 2003-02-25 | — | — | US | disclosed |
| EP-1046654-A1 | Olefin polymerization catalysts and olefin polymer production methods using said olefin polymerization catalysts | JSR Corporation (JP) | 2000-10-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131721-A1 | METHOD OF DEPROTECTION OF ALKYL ARYLAMINE ETHERS | NAT1, PNMT, AADAC | TSHR 226/4885TDP1 3055/4885CYP3A4 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.