Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL27917897 | 0.88 | LMNA (0.69) | LMNATSHRALOX12ACHEADRA2A | |
| Toluene SCHEMBL50431 | 0.88 | LMNA (0.69) | LMNATSHRALOX12ACHEADRA2A | |
| Toluene SCHEMBL28086966 | 0.88 | LMNA (0.69) | LMNATSHRALOX12ACHEADRA2A | |
| Toluene SCHEMBL6194164 | 0.88 | LMNA (0.69) | LMNATSHRALOX12ACHEADRA2A | |
| Toluene SCHEMBL11298633 | 0.86 | LMNA (0.65) | LMNATSHRALOX12ACHEADRA2A | |
| Toluene SCHEMBL246259 | 0.86 | LMNA (0.65) | LMNATSHRALOX12ACHEADRA2A | |
| Toluene SCHEMBL6795640 | 0.86 | LMNA (0.65) | LMNATSHRALOX12ACHEADRA2A | |
| Toluene SCHEMBL11305018 | 0.86 | LMNA (0.65) | LMNATSHRALOX12ACHEADRA2A | |
| Toluene SCHEMBL11305945 | 0.83 | LMNA (0.61) | LMNATSHRALOX12ACHEADRA2A | |
| Toluene SCHEMBL9191013 | 0.82 | LMNA (0.52) | LMNATSHRALOX12ACHEADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104072382-A | Synthetic process of crude meclofenoxate hydrochloride | JIANGSU HI STONE PHARMACEUTICAL CO LTD | 2014-10-01 | — | — | CN | disclosed |