Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | F13A1 | P00488 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TGM1 | P22735 | 1/20 | 0.31 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511134 | 0.89 | TGM2 (0.49) | TGM2ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL27965034 | 0.89 | TGM2 (0.41) | TGM2ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL27965032 | 0.86 | ALDH1A1 (0.52) | TGM2ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL28987056 | 0.84 | TGM2 (0.40) | TGM2ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL28987059 | 0.83 | TGM2 (0.47) | TGM2ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL30345122 | 0.81 | TGM2 (0.49) | TGM2ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL28987060 | 0.81 | TGM2 (0.49) | TGM2ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL28424528 | 0.81 | TGM2 (0.49) | TGM2ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL28049084 | 0.80 | TTR (0.40) | TGM2ALDH1A1MAPK1GAATTR | |
| SCHEMBL26534130 | 0.80 | TGM2 (0.45) | TGM2ALDH1A1TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103951578-A | Multifunctional acrylamide compound containing capsaicin-like functional structure and preparation method and application thereof | OCEAN UNIV CHINA | 2014-07-30 | — | — | CN | claimed |
| CN-103951578-A | Multifunctional acrylamide compound containing capsaicin-like functional structure and preparation method and application thereof | OCEAN UNIV CHINA | 2014-07-30 | — | — | CN | disclosed |