SCHEMBL28049084

SCHEMBL28049084

C=CC(=O)NCc1cc(C(=O)c2ccccc2)c(O)c(CNC(=O)C=C)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.40
KMT2A Q03164 3/20 0.39
GAA P10253 2/20 0.39
MEN1 O00255 2/20 0.39
USP2 O75604 1/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
LMNA P02545 1/20 0.39
AKT1 P31749 1/20 0.38
BCL2 P10415 1/20 0.38
MCL1 Q07820 1/20 0.38
TGM2 P21980 3/20 0.38
HMGB1 P09429 1/20 0.35
CXCL12 P48061 1/20 0.35
AKR1C3 P42330 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30442470 1.00 TTR (0.40) TTRKMT2AGAAMEN1USP2
SCHEMBL27978331 0.80 TGM2 (0.46) TTRKMT2AGAAALDH1A1LMNA
SCHEMBL14527868 0.77 MAPT (0.57) KMT2AGAAMEN1USP2KEAP1
SCHEMBL38655040 0.77 MAPT (0.48) KMT2AMEN1ALDH1A1HPGDLMNA
SCHEMBL9318439 0.76 ALDH1A1 (0.47) TTRKMT2AGAAMEN1USP2
SCHEMBL59858 0.72 TGM2 (0.55) KMT2AGAAALDH1A1HPGDLMNA
SCHEMBL2861278 0.72 BCL2 (0.53) KMT2AGAAMEN1USP2KEAP1
SCHEMBL3077592 0.72 BCL2 (0.45) KMT2AGAAMEN1USP2KEAP1
SCHEMBL27965032 0.72 ALDH1A1 (0.52) KMT2AGAAALDH1A1LMNATGM2
SCHEMBL15359166 0.72 TGM2 (0.44) KMT2AGAAMEN1USP2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105348131-A Reaction type ultraviolet light absorber as well as a preparation method and application thereof OCEAN UNIV CHINA 2016-02-24 CN claimed
CN-114058142-B Transparent fluorine-containing polymer film 浙江省化工研究院有限公司 2023-05-12 CN disclosed
CN-105348131-A Reaction type ultraviolet light absorber as well as a preparation method and application thereof OCEAN UNIV CHINA 2016-02-24 CN disclosed