Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 19/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 19/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6621005 | 0.90 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3662258 | 0.83 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL11578352 | 0.83 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL20555975 | 0.77 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL31041027 | 0.77 | SLC6A4 (0.47) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL4604800 | 0.77 | ALDH1A1 (0.64) | KDM4EMEN1NPC1MITFALDH1A1 | |
| SCHEMBL8553350 | 0.77 | SLC6A4 (0.51) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL15284826 | 0.76 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL4634790 | 0.76 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL7812359 | 0.75 | TACR1 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104428301-A | NAMPT inhibitors | ABBVIE INC | 2015-03-18 | — | — | CN | claimed |
| CN-104428301-A | NAMPT inhibitors | ABBVIE INC | 2015-03-18 | — | — | CN | disclosed |