SCHEMBL27979397

SCHEMBL27979397

CCCCCCOc1ccc(C23CC4CC(CC(C4)C2)C3)cc1-c1ccc2cc(C(=O)O)ccc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 10/20 0.55
RARG P13631 7/20 0.55
RARA P10276 4/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
NR1I2 O75469 1/20 0.55
LMNA P02545 1/20 0.55
PGR P06401 1/20 0.55
HSPD1 P10809 1/20 0.55
GOT1 P17174 1/20 0.55
GLRA1 P23415 1/20 0.55
BLM P54132 1/20 0.55
HSPE1 P61604 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
PPARG P37231 1/20 0.49
PPARD Q03181 1/20 0.49
PPARA Q07869 1/20 0.49
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48
KDM4E B2RXH2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL979218 0.85 RARB (0.72) RARBRARGRARAMEN1KMT2A
SCHEMBL980744 0.85 RARB (0.72) RARBRARGRARAMEN1KMT2A
SCHEMBL9300824 0.85 RARB (0.71) RARBRARGRARAMEN1KMT2A
SCHEMBL8766811 0.85 RARB (0.57) RARBRARGRARAMEN1KMT2A
SCHEMBL9331667 0.82 RARB (0.56) RARBRARGRARAMEN1KMT2A
SCHEMBL8458022 0.81 PTPN11 (0.44) RARBRARGRARAMEN1KMT2A
SCHEMBL7521122 0.80 MEN1 (0.61) RARBRARGRARAMEN1KMT2A
SCHEMBL8766205 0.78 RARG (0.69) RARBRARGRARAMEN1KMT2A
SCHEMBL9133374 0.78 RARA (0.55) RARBRARGRARAMEN1KMT2A
SCHEMBL29462757 0.78 RARG (0.69) RARBRARGRARAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104013540-A Composition comprising at least one naphthoic acid derivative and at least one compound of polyurethane polymer type or derivatives thereof, preparation processes therefor and uses thereof GALDERMA RES & DEV 2014-09-03 CN disclosed