Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25680688 | 0.90 | RAB9A (0.56) | RAB9AALDH1A1MAPTRAD51KMT2A | |
| SCHEMBL4733152 | 0.86 | ALDH1A1 (0.66) | RAB9AALDH1A1MAPTRAD51KMT2A | |
| SCHEMBL12549885 | 0.84 | RAB9A (0.88) | RAB9AALDH1A1MAPTRAD51KMT2A | |
| SCHEMBL27543086 | 0.84 | CYP1A2 (0.58) | RAB9AALDH1A1MAPTRAD51KMT2A | |
| SCHEMBL983506 | 0.84 | ALDH1A1 (0.68) | RAB9AALDH1A1MAPTRAD51KMT2A | |
| SCHEMBL8063648 | 0.83 | ALDH1A1 (0.82) | RAB9AALDH1A1MAPTRAD51KMT2A | |
| SCHEMBL9359349 | 0.81 | ALDH1A1 (0.64) | RAB9AALDH1A1MAPTRAD51KMT2A | |
| SCHEMBL6268237 | 0.81 | ALDH1A1 (0.64) | RAB9AALDH1A1MAPTRAD51KMT2A | |
| SCHEMBL16192982 | 0.81 | ALDH1A1 (0.64) | RAB9AALDH1A1MAPTRAD51KMT2A | |
| SCHEMBL18383716 | 0.80 | RAB9A (0.63) | RAB9AALDH1A1MAPTRAD51KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104177320-B | A kind of urea substituted biphenyl compounds and composition thereof and purposes | SUNSHINE LAKE PHARMA CO.,LTD. (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-104177320-A | Novel carbamide substituted biphenyl compound, composition and application thereof | GUANGDONG HEC PHARMACEUTICAL | 2014-12-03 | — | — | CN | disclosed |