Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL983506 | 0.88 | ALDH1A1 (0.68) | ALDH1A1MAPTRAB9ARAD51KMT2A | |
| SCHEMBL8063648 | 0.88 | ALDH1A1 (0.82) | ALDH1A1MAPTRAB9ARAD51KMT2A | |
| SCHEMBL27979591 | 0.86 | RAB9A (0.64) | ALDH1A1MAPTRAB9ARAD51KMT2A | |
| SCHEMBL9359349 | 0.85 | ALDH1A1 (0.64) | ALDH1A1MAPTRAB9ARAD51KMT2A | |
| SCHEMBL6268237 | 0.85 | ALDH1A1 (0.64) | ALDH1A1MAPTRAB9ARAD51KMT2A | |
| SCHEMBL12549885 | 0.85 | RAB9A (0.88) | ALDH1A1MAPTRAB9ARAD51KMT2A | |
| SCHEMBL16192982 | 0.85 | ALDH1A1 (0.64) | ALDH1A1MAPTRAB9ARAD51KMT2A | |
| SCHEMBL18383716 | 0.84 | RAB9A (0.63) | ALDH1A1MAPTRAB9ARAD51KMT2A | |
| Phenyl Phenylcarbamate SCHEMBL272994 | 0.84 | ALDH1A1 (0.76) | ALDH1A1MAPTRAB9ARAD51KMT2A | |
| SCHEMBL13104374 | 0.83 | RAB9A (0.64) | ALDH1A1MAPTRAB9ARAD51KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580553-B2 | Thermally-activated self-immolative materials | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-02-28 | — | — | US | disclosed |
| US-9580553-B2 | Thermally-activated self-immolative materials | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-02-28 | — | — | US | disclosed |
| US-20150368403-A1 | THERMALLY-ACTIVATED SELF-IMMOLATIVE MATERIALS | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2015-12-24 | — | — | US | disclosed |
| US-20150368403-A1 | THERMALLY-ACTIVATED SELF-IMMOLATIVE MATERIALS | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2015-12-24 | — | — | US | disclosed |
| WO-2014133620-A2 | THERMALLY-ACTIVATED SELF-IMMOLATIVE MATERIALS | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2014-09-04 | — | — | WO | disclosed |
| WO-2008053479-A9 | SELF-IMMOLATIVE POLYMERS | UNIV RAMOT (IL) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008053479-A1 | SELF-IMMOLATIVE POLYMERS | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2008-05-08 | — | — | WO | disclosed |
| WO-2008053479-A1 | SELF-IMMOLATIVE POLYMERS | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2008-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368403-A1 | THERMALLY-ACTIVATED SELF-IMMOLATIVE MATERIALS | PARG, PAICS, LRBA | ALDH1A1 2098/4885MAPT 215/4885RAB9A 1561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.