Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27817521 | 0.79 | PPIA (1.00) | PPIAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL5305401 | 0.78 | LMNA (0.60) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL10712905 | 0.76 | LMNA (0.64) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL27980329 | 0.76 | PPIA (1.00) | PPIAMAPTMEN1KMT2A | |
| SCHEMBL5335651 | 0.75 | LMNA (0.57) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL28785395 | 0.74 | PPIA (0.71) | PPIA | |
| SCHEMBL29273709 | 0.72 | MAPT (0.65) | PPIAMAPTMEN1KMT2ALMNA | |
| Iodide SCHEMBL7715449 | 0.70 | L3MBTL1 (0.58) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL5778368 | 0.69 | ALDH1A1 (0.53) | MAPTGAAMEN1KMT2ALMNA | |
| SCHEMBL27980140 | 0.69 | PPIA (1.00) | PPIAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103992245-A | Substituted urea compound and use thereof | UNIV EAST CHINA SCIENCE & TECH | 2014-08-20 | — | — | CN | disclosed |