SCHEMBL27980972

SCHEMBL27980972

CCCN(CCC)c1ccccc1Cc1ccccc1O

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.55
HTR1A P08908 1/20 0.53
KEAP1 Q14145 1/20 0.42
TSHR P16473 2/20 0.38
IDH1 O75874 1/20 0.38
NR1H2 P55055 1/20 0.37
NR1H3 Q13133 1/20 0.37
CYP2D6 P10635 1/20 0.37
HIF1A Q16665 1/20 0.37
POLB P06746 1/20 0.36
MAPK1 P28482 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
AKR1B1 P15121 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL814319 0.89 HTR1A (0.40) HSPA5HTR1A
SCHEMBL1837510 0.81 HTR1A (0.48) HTR1ATSHRHIF1APOLB
SCHEMBL8677571 0.78 HSPA5 (0.64) HSPA5HTR1AKEAP1TSHRCYP2D6
SCHEMBL30462984 0.77 HTR1A (0.40) HTR1A
Bromide SCHEMBL10963850 0.77 DRD2 (0.46) TSHR
SCHEMBL1534143 0.76 HTR1A (0.43) HTR1ATAAR1
SCHEMBL6880642 0.75 LMNA (0.44) HTR1ATSHRNR1H2NR1H3POLB
SCHEMBL7150417 0.74 TP53 (0.41) HTR1A
SCHEMBL11724744 0.74 HTR1A (0.38) HTR1A
SCHEMBL6880657 0.74 HTR1A (0.46) HTR1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102471244-B Process for producing N-substituted carbamate, process for producing isocyanate using the N-substituted carbamate, and composition for transporting and storing N-substituted carbamate containing N-substituted carbamate and aromatic hydroxy compound ASAHI CHEMICAL CORP 2014-09-24 CN disclosed