SCHEMBL27980997

SCHEMBL27980997

Cc1cc(Cl)cc(C(=O)OCO)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.40
ALDH1A1 P00352 6/20 0.40
GAA P10253 6/20 0.40
GLA P06280 4/20 0.40
HPGD P15428 5/20 0.39
ABCB1 P08183 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA7 P43166 2/20 0.37
CA9 Q16790 2/20 0.37
CA14 Q9ULX7 2/20 0.37
MAPK1 P28482 1/20 0.36
METTL3 Q86U44 1/20 0.36
MAOB P27338 1/20 0.36
MCL1 Q07820 1/20 0.36
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2657833 0.80 ABL1 (0.47) ALDH1A1GAANPSR1SMN1; SMN2CA12
SCHEMBL27980809 0.74 METTL3 (0.43) KDM4EALDH1A1CA12CA1CA2
SCHEMBL8148635 0.74 CYP3A4 (0.59) KDM4EALDH1A1HPGDSMN1; SMN2CA1
SCHEMBL27508874 0.74 CYP3A4 (0.39) KDM4EALDH1A1HPGDABCB1MCL1
SCHEMBL25234783 0.72 CA1 (0.51) KDM4EALDH1A1SMN1; SMN2CA12CA1
SCHEMBL9268795 0.72 ABCB1 (0.48) KDM4EALDH1A1ABCB1SMN1; SMN2CA12
SCHEMBL16529438 0.71 ALDH1A1 (0.55) KDM4EALDH1A1GAAGLAHPGD
SCHEMBL29682930 0.71 CYP3A4 (0.56) KDM4EALDH1A1GAAGLAHPGD
SCHEMBL8373456 0.71 CYP3A4 (0.56) KDM4EALDH1A1GAAGLAHPGD
SCHEMBL12466574 0.71 ALDH1A1 (0.49) KDM4EALDH1A1GAAGLAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102365255-B Method for producing alcohol compound and catalyst therefor SUMITOMO CHEMICAL CO 2015-01-07 CN disclosed
CN-102365254-B Method for producing alcohol compound SUMITOMO CHEMICAL CO 2014-08-27 CN disclosed