Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3573157 | 0.85 | CA12 (0.42) | ABCB1PDE3BPDE3ACA12CA1 | |
| SCHEMBL4314430 | 0.78 | ALDH1A1 (0.44) | CA1CA2MAPK1SMN1; SMN2TP53 | |
| SCHEMBL28460720 | 0.78 | LMNA (0.49) | ABCB1TSHRMAPTNPC1LMNA | |
| SCHEMBL16529438 | 0.78 | ALDH1A1 (0.55) | CA12CA1CA2CA9TSHR | |
| SCHEMBL23023522 | 0.77 | EZH2 (0.39) | ABCB1KMT2ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL11014756 | 0.76 | ALDH1A1 (0.49) | ABCB1CA12CA1CA2CA7 | |
| SCHEMBL28449266 | 0.76 | ABCB1 (0.37) | ABCB1TSHRKMT2AKDM4EMAPT | |
| SCHEMBL8086920 | 0.75 | KDM4E (0.59) | PDE3BPDE3ACA12CA1CA2 | |
| SCHEMBL16509646 | 0.74 | CYP3A4 (0.58) | ABCB1CA12CA1CA2CA7 | |
| SCHEMBL29606644 | 0.74 | CXCR2 (0.41) | ABCB1MAPK1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024395-A1 | QUINOLINE DERIVATIVES AS IMMUNOMODULATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |