Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NOS1 | P29475 | 3/20 | 0.46 |
| ▸ | NOS2 | P35228 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943401 | 0.80 | PDE10A (0.56) | PDE10AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27335197 | 0.80 | PDE10A (0.56) | PDE10AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6431603 | 0.77 | PDE10A (0.60) | PDE10AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL22119735 | 0.76 | PDE10A (0.59) | PDE10AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28282006 | 0.75 | PDE10A (0.62) | PDE10AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11326420 | 0.74 | PDE10A (0.61) | PDE10AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27798082 | 0.73 | GSK3B (0.64) | PDE10AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27098919 | 0.72 | ALDH1A1 (0.51) | PDE10AMEN1KMT2AALDH1A1MAPT | |
| Tetramethylammonium Ion SCHEMBL8838445 | 0.72 | PDE10A (0.54) | PDE10AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL949962 | 0.72 | PDE10A (1.00) | PDE10AMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103998040-A | Alkyne substituted quinazoline compound and methods of use | NEWGEN THERAPEUTICS INC | 2014-08-20 | — | — | CN | disclosed |