Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL1716795 | 0.78 | — | — | |
| Methyl Alcohol SCHEMBL28032140 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL22444763 | 0.71 | TRPA1 (0.50) | TSHRACHECYP1A2 | |
| Ammonia Solution, Strong SCHEMBL15862222 | 0.71 | TRPA1 (0.50) | TSHRACHECYP1A2 | |
| SCHEMBL27859301 | 0.70 | CD274 (0.38) | CD274PDCD1CYP3A4TSHRPIK3CA | |
| SCHEMBL30340550 | 0.69 | ALDH1A1 (0.46) | CD274PDCD1CYP3A4TSHRPIK3CA | |
| Ethylamine SCHEMBL15052268 | 0.69 | CYP3A4 (0.41) | CD274PDCD1CYP3A4TSHRPIK3CA | |
| SCHEMBL21616726 | 0.69 | ALDH1A1 (0.46) | CD274PDCD1CYP3A4TSHRPIK3CA | |
| SCHEMBL30834716 | 0.67 | TRPA1 (0.52) | TSHRACHECYP1A2 | |
| SCHEMBL218508 | 0.67 | TRPA1 (0.52) | TSHRACHECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102325753-B | Carbazole carboxamide compounds useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2014-09-10 | — | — | CN | disclosed |