Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.49 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2799733 | 0.87 | KCNH2 (0.49) | HTR1ADRD2HTR2AKCNH2KCNQ1 | |
| Hydrochloric Acid SCHEMBL2799550 | 0.86 | KCNH2 (0.48) | HTR1ADRD2HTR2AKCNH2KCNQ1 | |
| SCHEMBL2798290 | 0.81 | KCNH2 (0.64) | HTR1ADRD2HTR2AKCNH2KCNQ1 | |
| Hydrochloric Acid SCHEMBL2799106 | 0.80 | KCNH2 (0.37) | HTR1ADRD2HTR2AKCNH2 | |
| SCHEMBL4757688 | 0.78 | KCNH2 (0.57) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL2800075 | 0.78 | KCNH2 (0.51) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL2798725 | 0.78 | KCNH2 (0.70) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL16463812 | 0.77 | KCNH2 (0.48) | HTR1ADRD2HTR2AKCNH2KCNQ1 | |
| Hydrochloric Acid SCHEMBL2795099 | 0.77 | KCNH2 (0.51) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL2799592 | 0.77 | KCNH2 (0.48) | HTR1ADRD2HTR2AKCNH2KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524738-B2 | Quinolinones and quinoxalinones as antibacterial composition | TOYAMA CHEMICAL CO., LTD. (JP) | 2013-09-03 | — | — | US | disclosed |
| US-8329694-B2 | Quinoxalinones as antibacterial composition | TOYAMA CHEMICAL CO., LTD. (JP) | 2012-12-11 | — | — | US | disclosed |
| US-20120214990-A1 | QUINOLINONES AND QUINOXALINONES AS ANTIBACTERIAL COMPOSITION | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-08-23 | — | — | US | disclosed |
| EP-2468743-A1 | Nitrogen-containing bicyclic compounds useful as antibacterial agents | Toyama Chemical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |
| US-20100168418-A1 | NOVEL NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-07-01 | — | — | US | disclosed |
| EP-1900732-A1 | NOVEL NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2008-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168418-A1 | NOVEL NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF | ROS1, NOX1, ARG1 | HTR1A 3839/4885DRD2 873/4885HTR2A 4495/4885 |
| US-20120214990-A1 | QUINOLINONES AND QUINOXALINONES AS ANTIBACTERIAL COMPOSITION | NQO2, ASNS, NDUFS1 | HTR1A 4059/4885DRD2 2745/4885HTR2A 4099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.