SCHEMBL27984366

SCHEMBL27984366

CCCC(CCCC(=O)O)c1c[nH]c2cc(Cl)c(Br)cc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
GSK3B P49841 1/20 0.40
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38
CSNK2A1 P68400 1/20 0.38
CYSLTR2 Q9NS75 1/20 0.37
CYSLTR1 Q9Y271 1/20 0.37
PRKAB2 O43741 3/20 0.34
PRKAG1 P54619 3/20 0.34
PRKAA2 P54646 3/20 0.34
PRKAA1 Q13131 3/20 0.34
PRKAG3 Q9UGI9 3/20 0.34
PRKAG2 Q9UGJ0 3/20 0.34
PRKAB1 Q9Y478 3/20 0.34
PTGFR P43088 3/20 0.33
CYP3A4 P08684 1/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27400767 0.76 GPR84 (0.59) CYP1A2CYSLTR2CYSLTR1CYP3A4ALDH1A1
Butyric Acid SCHEMBL433437 0.76 CYP1A2 (0.46) CYP1A2GSK3BCSNK2A1PRKAB2PRKAG1
Decanoic Acid SCHEMBL4214099 0.76 CYP1A2 (0.42) CYP1A2GSK3BMTNR1ACSNK2A1ALDH1A1
Nonanoate SCHEMBL27808330 0.76 CYP1A2 (0.42) CYP1A2GSK3BMTNR1ACSNK2A1ALDH1A1
Palmitic Acid SCHEMBL432626 0.76 CYP1A2 (0.42) CYP1A2GSK3BMTNR1ACSNK2A1ALDH1A1
Octanoic Acid SCHEMBL435382 0.76 CYP1A2 (0.42) CYP1A2GSK3BMTNR1ACSNK2A1ALDH1A1
SCHEMBL19708399 0.69 CSNK2A1 (0.49) CYP1A2GSK3BMTNR1AMTNR1BCSNK2A1
Octanoic Acid SCHEMBL3890252 0.68 TRPV1 (0.37) CYP1A2GSK3BMTNR1ACSNK2A1ALDH1A1
SCHEMBL8800942 0.68 CSNK2A1 (0.58) CYP1A2GSK3BMTNR1AMTNR1BCSNK2A1
SCHEMBL15300738 0.66 PRKAB2 (0.59) CSNK2A1PRKAB2PRKAG1PRKAA2PRKAA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102016063-B Choline esterase inhibitory substance detection device, detection kit and detection method INST OF MICROCHEMICAL TECHNOLOGY CO LTD 2014-09-17 CN disclosed