Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3983002 | 0.89 | NR4A2 (0.50) | LMNATSHRNR4A2ALDH1A1CFTR | |
| SCHEMBL25514681 | 0.80 | PTGS2 (0.39) | LMNATSHRNR4A2ALDH1A1CFTR | |
| SCHEMBL25514677 | 0.75 | ALDH1A1 (0.50) | TSHRALDH1A1HSD17B10KDM4EPOLB | |
| SCHEMBL8887417 | 0.75 | LMNA (0.47) | LMNATSHRNR4A2ALDH1A1CFTR | |
| SCHEMBL20068336 | 0.75 | MYC (0.49) | LMNATSHRNR4A2ALDH1A1CFTR | |
| SCHEMBL1878367 | 0.74 | KDM4E (0.49) | LMNATSHRALDH1A1CFTRHSD17B10 | |
| Dimethyl Phthalate SCHEMBL29500970 | 0.74 | TSHR (0.74) | LMNATSHRALDH1A1CFTRHSD17B10 | |
| Dimethyl Phthalate SCHEMBL790124 | 0.74 | TSHR (0.74) | LMNATSHRALDH1A1CFTRHSD17B10 | |
| Dimethyl Phthalate SCHEMBL34630 | 0.74 | TSHR (0.74) | LMNATSHRALDH1A1CFTRHSD17B10 | |
| Dimethyl Phthalate SCHEMBL29669976 | 0.74 | TSHR (0.74) | LMNATSHRALDH1A1CFTRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304130-A | MCL-1 inhibitors | 吉利德科学公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-112118845-B | MCL-1 inhibitors | 吉利德科学公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-110381738-B | Pesticidal and parasiticidal vinyl isoxazoline compounds | 勃林格殷格翰动物保健美国公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-112118845-A | MCL-1 inhibitors | 吉利德科学公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-104066330-A | Isoxazoline derivatives for controlling ectoparasites | LILLY CO ELI | 2014-09-24 | — | — | CN | disclosed |