SCHEMBL27985233

SCHEMBL27985233

CS(=O)(=O)c1cncnc1C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.38
P4HTM Q9NXG6 2/20 0.32
ATR Q13535 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 1/20 0.31
NAPRT Q6XQN6 1/20 0.31
BCAT2 O15382 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29957082 0.72 HCAR2 (0.43) HCAR2P4HTMMEN1KMT2AKDM4E
SCHEMBL3561461 0.72 HCAR2 (0.43) HCAR2P4HTMMEN1KMT2AKDM4E
SCHEMBL8148245 0.72 CYP17A1 (0.37)
SCHEMBL19268308 0.72 HCAR2 (0.39) HCAR2MEN1KMT2AKDM4ENAPRT
SCHEMBL1252476 0.70 KDM4E (0.53) P4HTMKDM4ENAPRTBCAT2
SCHEMBL28022095 0.70 HCAR2 (0.38) HCAR2MEN1KMT2AKDM4ENAPRT
SCHEMBL629032 0.70 HCAR2 (0.44) HCAR2P4HTMMEN1KMT2AKDM4E
SCHEMBL68960 0.70 KDM4E (0.47) HCAR2MEN1KMT2AKDM4ENAPRT
SCHEMBL30978924 0.70 HCAR2 (0.44) HCAR2P4HTMMEN1KMT2AKDM4E
SCHEMBL352483 0.70 SPR (0.45) HCAR2P4HTMMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104203925-A 5-aminopyrimidine derivatives and use thereof for combating undesired plant growth BAYER IP GMBH 2014-12-10 CN disclosed