Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19268308 | 0.87 | HCAR2 (0.39) | HCAR2MEN1KMT2AKDM4ENAPRT | |
| SCHEMBL31446350 | 0.79 | ASPH (0.43) | HCAR2KDM4E | |
| SCHEMBL29957082 | 0.72 | HCAR2 (0.43) | HCAR2MEN1KMT2AKDM4ENAPRT | |
| SCHEMBL3561461 | 0.72 | HCAR2 (0.43) | HCAR2MEN1KMT2AKDM4ENAPRT | |
| SCHEMBL13765814 | 0.70 | LMNA (0.39) | KDM4E | |
| SCHEMBL27985233 | 0.70 | HCAR2 (0.38) | HCAR2MEN1KMT2AKDM4ENAPRT | |
| SCHEMBL31358930 | 0.70 | KDM4E (0.37) | HCAR2KMT2AKDM4E | |
| SCHEMBL68960 | 0.70 | KDM4E (0.47) | HCAR2MEN1KMT2AKDM4ENAPRT | |
| SCHEMBL30978924 | 0.70 | HCAR2 (0.44) | HCAR2MEN1KMT2AARKDM4E | |
| SCHEMBL629032 | 0.70 | HCAR2 (0.44) | HCAR2MEN1KMT2AARKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947292-B | nitrogen-containing heteroaryl compounds | HOFFMAN-LA ROCHE LTD. (CH) | 2015-08-19 | — | — | CN | disclosed |