Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 5/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | IAPP | P10997 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21154074 | 0.89 | HTR2B (0.49) | MPOSLC6A4TAAR1ALDH1A1CYP3A4 | |
| SCHEMBL11060991 | 0.80 | ALDH1A1 (0.61) | ALDH1A1CYP3A4ALOX15USP2HPGD | |
| SCHEMBL4967651 | 0.80 | TAAR1 (0.65) | MPOSLC6A4TAAR1MGLLHSPA5 | |
| SCHEMBL11131843 | 0.79 | HSPA5 (0.58) | TAAR1TDP1HTR2BHSPA5TSHR | |
| SCHEMBL38663341 | 0.79 | TAAR1 (0.46) | TAAR1ALDH1A1CYP3A4ALOX15USP2 | |
| SCHEMBL10438887 | 0.78 | TAAR1 (0.62) | MPOSLC6A4TAAR1MGLLHSPA5 | |
| SCHEMBL7094868 | 0.76 | ALDH1A1 (0.67) | ALDH1A1CYP3A4ALOX15USP2HPGD | |
| SCHEMBL3800530 | 0.76 | TAAR1 (0.65) | MPOSLC6A4TAAR1MGLLHSPA5 | |
| SCHEMBL11629972 | 0.75 | HSPA5 (0.52) | TAAR1TDP1HTR2BHSPA5TSHR | |
| SCHEMBL7093157 | 0.74 | ALDH1A1 (0.70) | ALDH1A1CYP3A4ALOX15USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103073554-B | Substituted pyrrole chromone compound | SUN YAT-SEN UNIVERSITY (CN) | 2014-10-29 | — | — | CN | disclosed |