SCHEMBL11629972

SCHEMBL11629972

O[Si](O)(O)O.Oc1ccccc1Cc1ccco1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.52
KEAP1 Q14145 1/20 0.43
GFER P55789 1/20 0.39
HIF1A Q16665 2/20 0.38
CYP2D6 P10635 1/20 0.38
TSHR P16473 1/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
MAPT P10636 2/20 0.37
TAAR1 Q96RJ0 1/20 0.37
AKR1B1 P15121 1/20 0.37
HTR2B P41595 1/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GAA P10253 1/20 0.37
HTT P42858 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11131843 0.94 HSPA5 (0.58) HSPA5KEAP1HIF1ACYP2D6TSHR
SCHEMBL21154074 0.78 HTR2B (0.49) HSPA5HIF1ACYP2D6TSHRMEN1
SCHEMBL29975956 0.75 LMNA (0.41) HSPA5HIF1ATSHRMEN1KMT2A
SCHEMBL27985442 0.75 MPO (0.46) HSPA5HIF1ACYP2D6TSHRTAAR1
SCHEMBL6732302 0.75 LMNA (0.41) HSPA5HIF1ATSHRMEN1KMT2A
SCHEMBL30576429 0.75 ALOX5 (0.53) TSHRMEN1KMT2AMAPTLMNA
SCHEMBL1846967 0.75 ALOX5 (0.53) TSHRMEN1KMT2AMAPTLMNA
SCHEMBL22443868 0.74 TSHR (0.66) HIF1ACYP2D6TSHRMEN1KMT2A
SCHEMBL11717208 0.74 IDO1 (0.47) HSPA5KEAP1HIF1ACYP2D6TSHR
SCHEMBL7364036 0.73 MEN1 (0.38) TSHRMEN1KMT2AMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4125703-A Process for the production of phenol silicate compounds and their condensation products BLOUNT DAVID H 1978-11-14 US claimed
US-4125703-A Process for the production of phenol silicate compounds and their condensation products BLOUNT DAVID H 1978-11-14 US disclosed