Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 8/20 | 0.41 |
| ▸ | HTR2A | P28223 | 6/20 | 0.41 |
| ▸ | HTR2B | P41595 | 6/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | LATS1 | O95835 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985661 | 1.00 | RAD52 (0.47) | RAD52ADRB1HTR2CHTR2AHTR2B | |
| SCHEMBL335553 | 0.83 | ADRB1 (0.57) | RAD52ADRB1HTR2CHTR2AHTR2B | |
| SCHEMBL23777830 | 0.83 | ADRB1 (0.57) | RAD52ADRB1HTR2CHTR2AHTR2B | |
| SCHEMBL23777738 | 0.83 | ADRB1 (0.57) | RAD52ADRB1HTR2CHTR2AHTR2B | |
| SCHEMBL30996886 | 0.83 | ADRB1 (0.57) | RAD52ADRB1HTR2CHTR2AHTR2B | |
| SCHEMBL17884782 | 0.82 | CHRNB2 (0.54) | RAD52GSK3BLATS1ROCK2ROCK1 | |
| SCHEMBL30609705 | 0.82 | CHRNB2 (0.54) | RAD52GSK3BLATS1ROCK2ROCK1 | |
| SCHEMBL4025392 | 0.82 | ADRB1 (0.52) | RAD52ADRB1HTR2CHTR2AHTR2B | |
| SCHEMBL22542046 | 0.82 | ADRB1 (0.52) | RAD52ADRB1HTR2CHTR2AHTR2B | |
| SCHEMBL22542020 | 0.82 | ADRB1 (0.52) | RAD52ADRB1HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102239152-B | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP. (JP) | 2014-10-29 | — | — | CN | disclosed |