Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320363 | 0.88 | MAPT (0.44) | MAPTTSHRKDM4ESMN1; SMN2CHRNB2 | |
| SCHEMBL28643566 | 0.79 | MAPT (0.34) | MAPTALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL5853465 | 0.77 | ALDH1A1 (0.39) | GAAALDH1A1TSHRKDM4ESMN1; SMN2 | |
| Sulfuric Acid SCHEMBL29200168 | 0.75 | SPHK1 (0.39) | MAPTTSHRHPGD | |
| SCHEMBL8061822 | 0.72 | SLC6A2 (0.30) | — | |
| SCHEMBL2621579 | 0.72 | ALDH1A1 (0.43) | GAAALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL28644987 | 0.72 | SPHK1 (0.33) | MAPTTSHRHPGD | |
| SCHEMBL7358818 | 0.72 | LMNA (0.43) | MAPTALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL27323897 | 0.71 | ALDH1A1 (0.42) | MAPTGAAALDH1A1TSHRKDM4E | |
| Hydrochloric Acid SCHEMBL30902051 | 0.69 | ALDH1A1 (0.41) | MAPTGAAALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104245683-A | Cyclic amine compounds, compositions, and polyurethane foams made therefrom | DOW GLOBAL TECHNOLOGIES LLC | 2014-12-24 | — | — | CN | disclosed |