Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9389629 | 0.98 | LTA4H (0.36) | LTA4HPCSK9MEN1KMT2APTGS2 | |
| Bromide SCHEMBL29066404 | 0.96 | LTA4H (0.35) | LTA4HPCSK9MEN1KMT2APTGS2 | |
| Bromide SCHEMBL28050098 | 0.96 | DNM1 (0.36) | LTA4HPCSK9MEN1KMT2APTGS2 | |
| SCHEMBL129711 | 0.96 | LTA4H (0.38) | LTA4HPCSK9MEN1KMT2APTGS2 | |
| Iodide SCHEMBL23668714 | 0.93 | LTA4H (0.36) | LTA4HPCSK9MEN1KMT2APTGS2 | |
| Phosphine SCHEMBL28009253 | 0.93 | LTA4H (0.36) | LTA4HPCSK9MEN1KMT2APTGS2 | |
| Water SCHEMBL27533065 | 0.93 | LTA4H (0.36) | LTA4HPCSK9MEN1KMT2APTGS2 | |
| Fluoride SCHEMBL28402422 | 0.93 | LTA4H (0.36) | LTA4HPCSK9MEN1KMT2APTGS2 | |
| Hydrochloric Acid SCHEMBL17263858 | 0.93 | LTA4H (0.36) | LTA4HPCSK9MEN1KMT2APTGS2 | |
| Bromide SCHEMBL28284782 | 0.92 | MEN1 (0.40) | MEN1KMT2ASMN1; SMN2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114516949-B | Crystallization-resistant modified epoxy resin for joint beautifying agent and preparation method and application thereof | 南通星辰合成材料有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-104231229-A | Preparation method of brominated epoxy resin special for copper-clad plate and product prepared by using preparation method | KINGBOARD FANYU NANSHA PETROCHEMICAL COMPANY LTD | 2014-12-24 | — | — | CN | claimed |
| CN-114517000-B | Epoxy resin for electrical castable and preparation method and application thereof | 南通星辰合成材料有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-114516949-B | Crystallization-resistant modified epoxy resin for joint beautifying agent and preparation method and application thereof | 南通星辰合成材料有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-114516949-B | Crystallization-resistant modified epoxy resin for joint beautifying agent and preparation method and application thereof | 南通星辰合成材料有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-110343365-A | A kind of copper-clad plate high CTI epoxy resin and preparation method thereof | 建滔(广州)高新材料有限公司 | 2019-10-18 | — | — | CN | disclosed |