Phosphine

Phosphine

SCHEMBL28009253

CCCC[PH](c1ccccc1)(c1ccccc1)c1ccccc1.P

nearest known ligand 0.43

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.36
PCSK9 Q8NBP7 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PTGS2 P35354 1/20 0.35
HDAC3 O15379 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
ESR1 P03372 1/20 0.34
TP53 P04637 1/20 0.33
EPHX2 P34913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL29066404 0.98 LTA4H (0.35) LTA4HPCSK9MEN1KMT2APTGS2
Hydrochloric Acid SCHEMBL28337796 0.98 LTA4H (0.35) LTA4HPCSK9MEN1KMT2APTGS2
SCHEMBL129711 0.98 LTA4H (0.38) LTA4HPCSK9MEN1KMT2APTGS2
Iodide SCHEMBL23668714 0.95 LTA4H (0.36) LTA4HPCSK9MEN1KMT2APTGS2
Water SCHEMBL27533065 0.95 LTA4H (0.36) LTA4HPCSK9MEN1KMT2APTGS2
Hydrochloric Acid SCHEMBL17263858 0.95 LTA4H (0.36) LTA4HPCSK9MEN1KMT2APTGS2
Bromide SCHEMBL9389629 0.95 LTA4H (0.36) LTA4HPCSK9MEN1KMT2APTGS2
Fluoride SCHEMBL28402422 0.95 LTA4H (0.36) LTA4HPCSK9MEN1KMT2APTGS2
Bromide SCHEMBL27985990 0.93 LTA4H (0.35) LTA4HPCSK9MEN1KMT2APTGS2
Bromide SCHEMBL28050098 0.93 DNM1 (0.36) LTA4HPCSK9MEN1KMT2APTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103922975-B Synthesis method of sulfonamide compound NANTONG VOLANT CHEM CORP 2015-06-17 CN claimed
CN-104497494-A High stably dispersed nano-silica filled epoxy resin system, cured product and preparation method thereof UNIV SHANGHAI 2015-04-08 CN claimed
CN-107349754-A A kind of desulfurizing agent composition and sulfur method 重庆千卡科技有限公司 2017-11-17 CN disclosed
CN-104448899-B Sulfuryl-containing two-photon fluorescent dyes 河南师范大学 2017-02-01 CN disclosed
CN-106189084-A A kind of method preparing brominated epoxy resin 江苏扬农锦湖化工有限公司 2016-12-07 CN disclosed
CN-103922975-B Synthesis method of sulfonamide compound NANTONG VOLANT CHEM CORP 2015-06-17 CN disclosed
CN-104497494-A High stably dispersed nano-silica filled epoxy resin system, cured product and preparation method thereof UNIV SHANGHAI 2015-04-08 CN disclosed
CN-104448899-A Sulfuryl-containing two-photon fluorescent dyes UNIV HENAN NORMAL 2015-03-25 CN disclosed