Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | ACP3 | P15309 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29624531 | 0.85 | IDO1 (0.54) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL28743534 | 0.85 | IDO1 (0.54) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL28743537 | 0.85 | IDO1 (0.54) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL39835 | 0.82 | TAAR1 (0.56) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL5703037 | 0.82 | IDO1 (0.59) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL3636562 | 0.81 | TAAR1 (0.55) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL1330066 | 0.81 | TAAR1 (0.55) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL6264578 | 0.81 | HTR2A (0.56) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL9802295 | 0.78 | IDO1 (0.54) | TAAR1IDO1HTR2AHTR2BHTR2C | |
| SCHEMBL1048398 | 0.78 | IDO1 (0.54) | TAAR1IDO1HTR2AHTR2BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101952244-B | N,N-disubstituted aminoalkylbiphenyl antagonists of prostaglandin D2 receptors | AMIRA PHARMACEUTICALS INC | 2014-11-05 | — | — | CN | disclosed |